Mutant ID Gene size POI Gene description MT# Rv# Phenotype Essential?
H14 1271 210 PPE family protein  (PPE) 1850 1801 Not-Attenuated Not-Essential
H15 1973 838 cation transporting ATPase, E1-E2 family ctpD 1515 1469 Not-Attenuated Not-Essential
H18 965 746 cyclopropane-fatty-acyl-phospholipid synthase 2 (cmaA2) 524 503 Not-Attenuated Not-Essential
H22 1676 60 PE_PGRS 2036 1983 Not-Attenuated Not-Essential
H28 2381 322 GTP pyrophosphokinase (relA) 2660 2583 Attenuated Essential 
H85 449 319 DNA binding protein, putative 2005 1956 Not-Attenuated Not-Essential
H106 899 632 HP 1551 1502 Not-Attenuated Not-Essential
H125 611 418 IS1537, resolvase 3936 3828 Not-Attenuated Not-Essential
H129 860 62 HP 3068 2990 Not-Attenuated Not-Essential
H131 941 126 conserved HP 154 146 Not-Attenuated Not-Essential
H132 4541 631 ATP-dependent helicase, putative (lhr) 3395 3296 Not-Attenuated Not-Essential
H134 1196 17 conserved HP 115 106 Not-Attenuated Not-Essential
H136 542 76 HP 364 349 Not-Attenuated Not-Essential
H140 917 30 RNA pseudouridylate synthase family 3399 3300 Not-Attenuated Not-Essential
H143 1742 74 acyl-CoA synthase, FadD28 3011 2941 Not-Attenuated Not-Essential
H144 2519 459 Ferredoxin reductase, electron transfer 1987 1937 Not-Attenuated Not-Essential
H145 1346 1144 HP 3848 3740 Not-Attenuated Not-Essential
H151 626 462 MitM-related protein 344 329 Not-Attenuated Not-Essential
H154 392 253 Conserved HP 3472 3364 Not-Attenuated Not-Essential
H157 2099 279 Conserved HP 2794 2721 Not-Attenuated Not-Essential
H159 641 169 HP 3503 3395 Not-Attenuated Not-Essential
H160 1526 476 Phospholipase C (plcC) 2414 2349 Not-Attenuated Not-Essential
H162 974 240 Conserved HP 2787 2714 Not-Attenuated Not-Essential
H163 632 336 transcriptional regulator, TetR family 315 302 Not-Attenuated Not-Essential
H166 1643 76 Phosphoglucomutase (pgmA) 3153 3068 Not-Attenuated Not-Essential
H168 1940 859 FAD flavoprotein oxidase 262 248 Not-Attenuated Not-Essential
H169 524 85 Cobinamide/cobinamide phosphate guanylyltransferase (cobU) 267 254 Not-Attenuated Not-Essential
H170 617 65 Phosphatidylethanolamine binding protein (lppC) 1962 1911 Not-Attenuated Not-Essential
H173 1076 829 HP 953 926 Not-Attenuated Not-Essential
H174 977 56 Conserved HP 917 893 Not-Attenuated Not-Essential
H178 461 129 HP (b/w Rv1737/1738) 1780 1738 Not-Attenuated Not-Essential
H179 2271 1895 arylsulfatase (atsA) 738 711 Not-Attenuated Not-Essential
H180 1547 321 virulence factor mce protein  183 174 Not-Attenuated Not-Essential
H181 1217 682 penicillin binding protein 3433 3330 Not-Attenuated Not-Essential
H185 1367 1072 Conserved HP 1628 1592 Not-Attenuated Not-Essential
H187 716 310 Conserved HP 77 71 Not-Attenuated Not-Essential
H189 1349 103 sugar transporter family protein (kgtP) 3580 3476 Not-Attenuated Not-Essential
H191 857 624 HP 3569 3463 Not-Attenuated Not-Essential
H192 710 399 lipoprotein, putative (lpqD) 3497 3390 Not-Attenuated Not-Essential
H197 395 111 Conservative HP 2829 2759 Not-Attenuated Not-Essential
H198 1688 103 AMP-binding family protein (fadD34) 40 35 Not-Attenuated Not-Essential
H205 1982 282 Conserved HP 2410 2345 Not-Attenuated Not-Essential
H206 1277 1116 Conservative HP 3806 3703 Not-Attenuated Not-Essential
H215 410 125 protozoan/cianobacterial globin family protein (glbN) 1594 1542 Not-Attenuated Not-Essential
H224 3725 1738 ABC transporter, ATP-binding protein (HP) 204 194 Not-Attenuated Not-Essential
H234 1238 77 Degt/DnrJ/EryC1 family protein (HP) 3510 3402 Not-Attenuated Not-Essential
H245 3227 1514 HP 3583 3479 Not-Attenuated Not-Essential
H250 1811 1063 HP 1099 1069 Not-Attenuated Not-Essential
H251 668 56 HNH endonuclease family protein  2545 2469 Not-Attenuated Not-Essential
H252 455 226 HP 2315 2254 Not-Attenuated Not-Essential
H253 977 598 Conserved HP 2483 2410 Not-Attenuated Not-Essential
H254 743 586 serine exterase, cutinase family 3557 3451 Not-Attenuated Not-Essential
H262 500 350 HP   3838 3733 Not-Attenuated Not-Essential
H264 774 218 Conserved HP 1979 1927 Not-Attenuated Not-Essential
H266 1007 172 Quinone oxidoreductase, putative (qor) 1501 1454 Not-Attenuated Not-Essential
H267 1145 877 SPFH domain/Band 7 family protein 1533.2 1488 Not-Attenuated Not-Essential
H269 3479 896 transcriptional regulator, LuxR family 1402 1358 Not-Attenuated Not-Essential
H271 1058 727 HP 2785 2712 Not-Attenuated Not-Essential
H272 1421 1123 amidase family protein (amiC) 2956 2888 Not-Attenuated Not-Essential
H274 1697 1108 HP 1671 1635 Moderately-attenauated Essential
H278 4196 794 glycosyl hydrolase 676 648 Not-Attenuated Not-Essential
H279 722 312 proline-rich antigen (pra) 1109 1078 Not-Attenuated Not-Essential
H281 1214 867 virulence factor (mce2) 618 589 Not-Attenuated Not-Essential
H282 1166 531 HP 2329 2267 Not-Attenuated Not-Essential
H284 11355 7007 PPE 3458 3350 Not-Attenuated Not-Essential
H286 431 153 HP 1861 1813 Not-Attenuated Not-Essential
H287 962 64 D-amino acid oxidase 1956 1905 Not-Attenuated Not-Essential
H288 419 300 HP 1765 1724 Not-Attenuated Not-Essential
H289 752 564 Conserved HP 2749 2675 Not-Attenuated Not-Essential
H290 1721 273 GAF family protein 2086 2027 Not-Attenuated Not-Essential
H292 476 239 HP 2801.1 2730 Moderately-attenauated Essential
H293 1193 921 membrane protein, mmpL family (mmpL6) 1608 1557 Not-Attenuated Not-Essential
H295 1213 415 cysteine synthase, putative (cysM3) 871 848 Not-Attenuated Not-Essential
H296 395 112 Conserved HP 652 624 Not-Attenuated Not-Essential
H297 1811 43 Ser/Thr protein kinase (pknI) 2982 2914 Not-Attenuated Not-Essential
H298 374 235 Conserved HP 1172 1139 Not-Attenuated Not-Essential
H300 1094 66 Type I restriction system specificity protein 2831 2761 Not-Attenuated Not-Essential
H302 626 427 Transcriptional regulator, MarR family 48 42 Not-Attenuated Not-Essential
H306 992 36 ABC transporter, ATP binding protein 79 73 Not-Attenuated Not-Essential
H307 974 748 Conserved HP 2780 2707 Not-Attenuated Not-Essential
H308 218 154 HP (b/w Rv1139/1140) 1172.1 1139 Not-Attenuated Not-Essential
H310 545 123 HP    787 762 Not-Attenuated Not-Essential
H320 927 387 IS Mt 1 transposase (HP) 1184 1147 Not-Attenuated Not-Essential
H329 1799 488 HP 1556 1508 Not-Attenuated Not-Essential
H331 1340 1093 glutamine synthase (glnA2) 2280 2222 Not-Attenuated Not-Essential
H343 1100 787 Conserved HP 202 192 Not-Attenuated Not-Essential
H349 239 50 Conserved HP 1625 1590 Not-Attenuated Not-Essential
H356 4464 566 polyketide synthase (ppsE) 3005 2935 Not-Attenuated Not-Essential
H361 3341 919 Transcriptional regulator, LuxR family (HP)  2563 2488 Not-Attenuated Not-Essential
H365 341 67 Conserved HP 2883 2816 Not-Attenuated Not-Essential
H370 293 123 HP 2407 2342 Not-Attenuated Not-Essential
H376 1142 894 Conserved HP 2239 2184 Not-Attenuated Not-Essential
H383 438 339 transcriptional regulator, MerR family 3438 3334 Not-Attenuated Not-Essential
H388 3197 2589 Drug transporter 3337 3239 Not-Attenuated Not-Essential
H389 1391 715 PPE 105 96 Not-Attenuated Not-Essential
H391 1691 187 HP 3176 3091 Not-Attenuated Not-Essential
H392 1280 400 P450 heme-thiolate protein 1834 1785 Not-Attenuated Not-Essential
H394 1643 63 TPP requiring enzyme ilvG (acetoactate synthase) 1868 1820 Not-Attenuated Not-Essential
H407 431 333 HP 2674 2599 Not-Attenuated Not-Essential
H408 1616 586 HP 1223 1186 Not-Attenuated Not-Essential
H410 902 39 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase (linB) 2656 2579 Not-Attenuated Not-Essential
H411 1058 244 transcriptional regulator, AraC family (virS) 3167 3082 Not-Attenuated Not-Essential
H415 1427 426 amidase family protein (amiD) 3485 3375 Not-Attenuated Not-Essential
H421 1187 493 fatty acid-CoA racemase (mcr) 1176 1143 Not-Attenuated Not-Essential
H423 2585 609 amino peptidase N (pepD) 2542 2467 Not-Attenuated Not-Essential
H424 557 260 HP 769 743 Not-Attenuated Not-Essential
H426 1004 326 4-hydroxy-2-oxovalerate aldolase (mphE) 3575 3469 Not-Attenuated Not-Essential
H427 1160 737 PPE family protein (PPE) 1856.1 1808 Not-Attenuated Not-Essential
H432 1160 527 MutT/nudix family protein 3293 3199 Not-Attenuated Not-Essential
H433 809 586 conserved HP 462 446 Not-Attenuated Not-Essential
H437 413 39 HP 2992 2923 Not-Attenuated Not-Essential
H438 1190 144 oxidoreductase, pyridine nucleotide-disulphide family 1860 1812 Not-Attenuated Not-Essential
H439 1115 490 HP 1078 1048 Not-Attenuated Not-Essential
H445 1397 950 sulfatase family protein (atsG) 310 296 Moderately-attenuated Essential
H446 2906 2203 membrane protein, mmpL family (mmpL2) 528 507 Not-Attenuated Not-Essential
H447 776 395 HP 3947 3839 Not-Attenuated Not-Essential
H449 965 295 diacylglycerol kinase catalytic domain-containing protein 3314 3218 Not-Attenuated Not-Essential
H450 254 26 conserved HP 3292 3198 Not-Attenuated Not-Essential
H451 1031 747 N5, N10 methylene tetrahydromethaopterin reductase related protein 3621 3520 Not-Attenuated Not-Essential
H456 1157 507 acetate kinase (ackA) 422 409 Not-Attenuated Not-Essential
H457 1355 1110 conserved HP 501 483 Not-Attenuated Not-Essential
H471 968 48 Quinone oxidoreductase 157 149 Not-Attenuated Not-Essential
H472 1409 1181 HP 4002 3887 Not-Attenuated Not-Essential
H474 992 251 ABC transporter 79 73 Not-Attenuated Not-Essential
H476 1565 274 Conserved HP 23 20 Not-Attenuated Not-Essential
H478 3041 2737 PPE family protein 1969 1918 Not-Attenuated Not-Essential
H482 1283 340 cyclopropane-fattyacyl-phospholipid synthase 3823 3720 Not-Attenuated Not-Essential
H484 1232 968 acyl-CoA dehydrogenase (fadE21) 2859 2789 Not-Attenuated Not-Essential
H485 2432 1504 Penicillin binding protein 1 (ponA) 3784 3682 Not-Attenuated Not-Essential
H487 419 46 HP 2832 2762 Not-Attenuated Not-Essential
H490 734 96 conserved HP 190 181 Not-Attenuated Not-Essential
H491 7562 5881 peptide synthase (nrp) 110 101 Attenuated Essential
H493 144 15 HP 2527.1 2452 Not-Attenuated Not-Essential
H494 2339 3 formate dehydrogenase, alpha-subunit (fdhF) 2968 2900 Not-Attenuated Not-Essential
H495 1364 400 HP 3839 3734 Not-Attenuated Not-Essential
H496 7562 364 peptide synthase (nrp) 110 101 Attenuated Essential
H498 1715 1477 potassium-transporting ATPase, A subunit (kdpA) 1058 1029 Not-Attenuated Not-Essential
H500 695 369 enoyl-CoA hydratase/isomerase family protein (echA3) 660 632 Not-Attenuated Not-Essential
H501 6301 3939 polyketide synthase (pks5) 1578 1527 Not-Attenuated Not-Essential
H502 1175 298 HP 1025 996 Not-Attenuated Not-Essential
H503 2315 322 ATP dependent RNA helicase, DEAD/DEAH box family 3751 3649 Not-Attenuated Not-Essential
H508 1112 897 phosphate ABC transporter, phosphate binding protein (pstS) 959 932 Not-Attenuated Not-Essential
H510 2045 1128 sensory box protein/ anti-anti-sigma factor (rsbU) 1410 1364 Not-Attenuated Not-Essential
H511 1046 69 GDP-D-mannose dehydratase (gmdA) 1561 1511 Not-Attenuated Not-Essential
H513 401 210 HP 71 65 Not-Attenuated Not-Essential
H515 2633 1329 conserved HP 612 584 Not-Attenuated Not-Essential
H521 9500 6665 PPE 3453 3347 Not-Attenuated Not-Essential
H523 1487 1116 monoxygenase flavin binding family 3168 3083 Not-Attenuated Not-Essential
H533 1628 789 HP 3885 3776 Not-Attenuated Not-Essential
H542 1598 836 cpsY protein 826 806 Not-Attenuated Not-Essential
H587 1832 331 CbxX/CfgX -related protein 1847 1798 Attenuated Essential
H601 1481 11 malate: quinone oxireductase 2918 2852 Not-Attenuated Not-Essential
H604 2054 1185 LytR/CpsA/Psr family protein 844 822 Not-Attenuated Not-Essential
H614 356 55 HP 1775 Not-Attenuated Not-Essential
H616 389 221 HP 3462 3354 Not-Attenuated Not-Essential
H617 842 316 transcriptional regulator, TetR family 152 144 Not-Attenuated Not-Essential
H703 1160 300 acyl CoA dehydrogenase, fad E14 1388 1346 Not-Attenuated Not-Essential
H705 2720 192 ATP-dependent DNA helicase, DAD/DEAHBox 2153 2092 Not-Attenuated Not-Essential
H726 470 66 HP 1548 1499 Not-Attenuated Not-Essential
H728 1322 253 amino acid permease 2055 1999 Not-Attenuated Not-Essential
H731 866 234 PEG1/MEST protein 1882 1834 Not-Attenuated Not-Essential
H735 284 192 Conserved HP : multiple hits 1236 1198 Not-Attenuated Not-Essential
H741 695 291 HP 3306 3210 Attenuated Essential
H742 293 94 HP 3269 Not-Attenuated Not-Essential
H743 1457 276 sensor histidine kinase(phoR) 783 758 Moderately-attenauated Essential
H744 1226 832 conserved HP   490 473 Not-Attenuated Not-Essential
H745 1367 317 CBS domain protein 1890 1842 Not-Attenuated Not-Essential
H747 2615 2303 sensor histidine kinase (kpdD) 1057 1028 Moderately-attenauated Essential
H751 935 249 RNA pol. Sigma factor (sigC) (insertion is upstream of Rv2069) 2129 2069 Not-Attenuated Not-Essential
H758 443 233 HP 2978 2910 Not-Attenuated Not-Essential
H765 2837 2406 Conserved membrane protein, mmpL family (deleted in H37Rv) 1802 Not-Attenuated Not-Essential
H768 347 95 HP 3276 3188 Not-Attenuated Not-Essential
H770 623 45 Conserved HP 799 775 Not-Attenuated Not-Essential
H774 1793 177 very-long-chain acyl-CoA synthetase (fadD6) 1244 1206 Not-Attenuated Not-Essential
H775 683 144 immunogenic protein MPB64/MPT64 precursor 3121 3036 Not-Attenuated Not-Essential
H776 1016 224 oxidorectase, short chain, dehydrogenase/reductase family 455 439 Not-Attenuated Not-Essential
H778 836 448 Conserved HP 1102 1072 Not-Attenuated Not-Essential
H779 1217 166 PPE 1836 1787 Not-Attenuated Not-Essential
H784 1043 671 HP 816 791 Not-Attenuated Not-Essential
H798 1112 979 RNA pol. Sigma factor (sigG) 191 182 Not-Attenuated Not-Essential
H815 623 470 carbonic anhydrase 3694 3588 Not-Attenuated Not-Essential
H826 731 251 PPE 2167 2108 Not-Attenuated Not-Essential
H838 1217 138 P450 heme-thiolate protein 1295 1256 Not-Attenuated Not-Essential
H844 710 280 Conserved HP 2888 2821 Attenuated Essential
H846 1736 1495 Conserved HP (choD) 3517 3409 Not-Attenuated Not-Essential
H851 2567 1595 Conserved HP 1015 987 Not-Attenuated Not-Essential
H855 1040 409 PPE 1205 1168 Not-Attenuated Not-Essential
H859 1529 303 HP 3801 3698 Not-Attenuated Not-Essential
H872 437 236 HP 3369 3269 Not-Attenuated Not-Essential
H874 2021 967 Prolyl oligopeptidase family protein 473 457 Not-Attenuated Not-Essential
H881 578 281 HP 3595 3491 Not-Attenuated Not-Essential
H887 1226 390 sugar transporter family protein (nanT) 1953 1902 Not-Attenuated Not-Essential
H888 1349 634 HP 260 246 Not-Attenuated Not-Essential
H892 863 578 ABC transporter 3126 3041 Not-Attenuated Not-Essential
H893 1121 171 glycosyl transferase 1566 1516 Not-Attenuated Not-Essential
H900 1688 637 HP 2866 2797 Not-Attenuated Not-Essential
H901 1175 827 PPE 3209 3125 Not-Attenuated Not-Essential
H902 293 147 HP 2593.1 2517 Not-Attenuated Not-Essential
H905 656 257 conserved HP 449 434 Not-Attenuated Not-Essential
H906 560 271 HP 2043 1989 Not-Attenuated Not-Essential
G21 1703 1410 adenylate cyclase, putative 1362 1320 Not-Attenuated Not-Essential
G30 380 211 HP 148 140 Not-Attenuated Not-Essential
G40 941 472 HP 740 713 Not-Attenuated Not-Essential
G41 953 187 Methoxy mycolic acid synthase 2 (mmaA2) 672 644 Not-Attenuated Not-Essential
G43 1091 47 HP 848 826 Not-Attenuated Not-Essential
G44 1706 1 Acyl-CoA dehydrogenase (fadE4) 241 231 Not-Attenuated Not-Essential
G46 2900 560 Membrane protein MmpL11 212 202 Not-Attenuated Not-Essential
G53 890 541 Methoxy mycolic acid synthase 1 (mmaA1) 673 645 Not-Attenuated Not-Essential
G54 1511 1175 Substrate CoA-ligase 3174 3089 Not-Attenuated Not-Essential
G59 1142 548 Cellulase 67 62 Not-Attenuated Not-Essential
G60 1682 154 Sulfate transporter 1781 1739 Not-Attenuated Not-Essential
G62 2099 324 Conserved HP 1917 1868 Not-Attenuated Not-Essential
G66 1595 545 NADH dehydrogenase I, subunit N (nuoN) 3246 3158 Not-Attenuated Not-Essential
G69 1886 1613 GTP binding elongation factor family protein 1202 1165 Not-Attenuated Not-Essential
G73 794 343 Ribonuclease HII 2970 2902 Not-Attenuated Not-Essential
G74 2087 356 HP 2942 2875 Not-Attenuated Not-Essential
G77 1826 510 HP 203 193 Not-Attenuated Not-Essential
G79 1322 95 Thiolase 257 243 Not-Attenuated Not-Essential
G80 890 540 Conserved HP, truncation 2821 2751 Not-Attenuated Not-Essential
G100 290 109 Conserved HP 2420 2346 Not-Attenuated Not-Essential
G103 671 502 PPE family protein 2505 2430 Not-Attenuated Not-Essential
G104 1073 282 glycosyl transferase  1570 1520 Not-Attenuated Not-Essential
G107 3440 349 membrane protein, (mmpL12) 1573 1522 Not-Attenuated Not-Essential
G109 1439 442 mitR protein 68 63 Not-Attenuated Not-Essential
G111 1172 502 Acyl-CoA dehydrogenase (FadE9) 776 752 Not-Attenuated Not-Essential
G112 1556 1357 substrate CoA ligase 175 166 Not-Attenuated Not-Essential
G116 416 321 HP 2075 2019 Not-Attenuated Not-Essential
G118 845 102 Bem 46 protein 2364 2307 Not-Attenuated Not-Essential
G121 1115 295 PPE family protein 3987 3873 Not-Attenuated Not-Essential
G122 1268 518 HP 4000 3885 Not-Attenuated Not-Essential
G126 725 382 Nitrate reductase, gamma subunit 1201 1164 Not-Attenuated Not-Essential
G130 383 165 HP 641 611 Not-Attenuated Not-Essential
G137 1676 357 adenylate cyclase, putative 1361 no Rv Not-Attenuated Not-Essential
G150 752 411 Conserved HP 2749 2675 Not-Attenuated Not-Essential
G159 1253 59 Exonuclease SbcD-related protein 1314 1277 Not-Attenuated Not-Essential
G162 1406 1002 Acyl-CoA dehydrogenase (fadE24) 3226 3139 Not-Attenuated Not-Essential
G171 431 314 HP 1280 1242 Not-Attenuated Not-Essential
G175 767 545 HP 2051 1995 Not-Attenuated Not-Essential
G181 794 514 conserved HP 50 44 Not-Attenuated Not-Essential
G182 1919 516 ABC transporter 1867 1819 Not-Attenuated Not-Essential
G184 1772 557 Succinate dehydrogenase, flavoprotein subunit  3419 3318 Not-Attenuated Not-Essential
G189 1253 444 HP 3258 3169 Not-Attenuated Not-Essential
G190 1772 442 Succinate dehydrogenase, flavoprotein subunit (sdhA) 3419 3318 Not-Attenuated Not-Essential
G194 1385 619 P450 heme-thiolate protein 1439 1394 Not-Attenuated Not-Essential
G204 1277 872 putative oxidoreductase 398 385 Not-Attenuated Not-Essential
G205 1181 1021 HP 2847 2777 Not-Attenuated Not-Essential
G209 557 287 conserved HP 459 443 Not-Attenuated Not-Essential
G211 869 568 HP 54 48 Not-Attenuated Not-Essential
G279 3278 1651 transcriptional regulator, LuxR family 399 386 Not-Attenuated Not-Essential
G282 170 33 rubredoxin 3349 3251 Not-Attenuated Not-Essential
G318 4619 47 cation-transporting ATPase E1-E2 family 440 425 Not-Attenuated Not-Essential
G416 1346 288 nicotinate phosphoribosyltransferase, putative  1372 1330 Not-Attenuated Not-Essential
G432 1010 390 carboxyl esterase (ligG) 674 646 Not-Attenuated Not-Essential
G441 1157 4 rec F protein  3 3 Not-Attenuated Not-Essential
G442 866 347 CDP diacylglycerol serine (pssA) 452 436 Not-Attenuated Not-Essential
G444 1031 166 Heat shock gene transcriptional repressor (HrcA) 2443 2374 Not-Attenuated Not-Essential
G463 680 524 HP 239 229 Not-Attenuated Not-Essential
G476 2888 29 membrane protein, mmpL9 2402 2339 Not-Attenuated Not-Essential
G477 821 315 Conserved HP 1380 1339 Not-Attenuated Not-Essential
G483 713 506 Carboxymethylenebutenolidase, putative (HP) 2114 2054 Not-Attenuated Not-Essential
G493 350 238 HP 3976 3862 Not-Attenuated Not-Essential
G506 902 67 Haloalkane dehalogenase (HP) 2353 2296 Not-Attenuated Not-Essential
G510 1970 1444 HP 2140 2079 Not-Attenuated Not-Essential
G514 1811 112 Long chain fatty acid CoA ligase, putative 2242 2187 Not-Attenuated Not-Essential
G518 734 310 HP 187 178 Not-Attenuated Not-Essential
G519 795 74 HP 2616 2542 Not-Attenuated Not-Essential
G523 737 27 Conserved HP 3035 2959 Not-Attenuated Not-Essential
G526 1049 542 Conserved HP 78 72 Not-Attenuated Not-Essential
G527 311 38 HP 3545 3440 Not-Attenuated Not-Essential
G528 191 141 HP 2365 2307 Not-Attenuated Not-Essential
G531 1169 393 acyl-CoA-dehydrogenase 3374 3274 Not-Attenuated Not-Essential
G532 2876 1222 membrane protein, mmpL1 family 412 402 Not-Attenuated Not-Essential
G534 419 329 Aspartate 1-decarboxylase (panD) 3706.1 3601 Attenuated Essential
G536 1856 1242 Penicillin binding protein, putative (HP) 2933 2864 Not-Attenuated Not-Essential
G539 842 139 MaoC family protein (HP) 255 241 Not-Attenuated Not-Essential
G568 456 204 Conserved HP 2674.1 2600 Not-Attenuated Not-Essential
G576 284 95 Conserved HP 1618 1567 Moderately-attenauated Essential
G583 827 359 Acyltransferase family protein (HP) 1471 1428 Not-Attenuated Not-Essential
G584 452 6 Ferric uptake regulation protein (furA) 1960 1909 Not-Attenuated Not-Essential
G588 641 179 HP 2072 2016 Not-Attenuated Not-Essential
G589 2282 869 Cell division protein FtsH 3714 3610 Not-Attenuated Not-Essential
G590 698 345 HP 1306 1268 Not-Attenuated Not-Essential
G592 656 70 Succinyl-CoA-3-Ketoacid-Coenzyme A transferase 2578 2503 Not-Attenuated Not-Essential
G598 887 439 RNA pol sigma factor, putative (pvdS) 3329 3232 Not-Attenuated Not-Essential
G611 1256 920 Conserved HP 3027 2953 Not-Attenuated Not-Essential
G625 860 367 Oxidoreductase, short-chain dehydrogenase/reductase family 1914 1865 Not-Attenuated Not-Essential
G627 1280 519 esterase, putative (lipD) 1974 1923 Not-Attenuated Not-Essential
G628 228 165 SPFH domain/band 7 family protein (b/w Rv1489/14490) 1535 1489 Not-Attenuated Not-Essential
G641 1535 1257 conserved HP   3932 3824 Not-Attenuated Not-Essential
G643 533 55 RNA pol sigma 70 factor, ECF family  (sigL) 759 735 Not-Attenuated Not-Essential
G645 983 18 esterase (lipF) 3591 3487 Not-Attenuated Not-Essential
G646 1676 165 nitrate reductase, b-subunit (narH) 1199 1162 Not-Attenuated Not-Essential
G659 938 365 HP 3541 3435 Not-Attenuated Not-Essential
G671 710 358 Conserved HP 2262 2206 Not-Attenuated Not-Essential
G673 1166 384 oxidoreductase, putative 346 331 Not-Attenuated Not-Essential
G675 2414 837 Conserved HP 1915 1866 Not-Attenuated Not-Essential
G676 1124 651 conserved hypothetical transmembrane protein 3731 3629 Not-Attenuated Not-Essential
G678 725 443 N-acetylmuramyl-L-alanine amidase - related 3820 3717 Not-Attenuated Not-Essential
G682 1310 751 HP 3166 3081 Not-Attenuated Not-Essential
G686 647 284 ribosomal L25 family protein (rplY) 1043 1015 Not-Attenuated Not-Essential
G690 509 273 HP 281 268 Not-Attenuated Not-Essential
G697 1208 581 P450-heme thiolate protein 790 766 Not-Attenuated Not-Essential
G698 932 134 hydrolase, alpha/beta hydrolase fold family 3411 3312 Not-Attenuated Not-Essential
G704 230 177 HP 974 947 Not-Attenuated Not-Essential
G708 425 98 HP 1484 1439 Not-Attenuated Not-Essential
G716 1232 465 PPE 3844 3739 Not-Attenuated Not-Essential
G720 1064 276 non-specific lifpid transfer protein, possible (HP) 3622.1 3522 Not-Attenuated Not-Essential
G722 947 333 methoxy mycolic acid synthase 4  (mmaA4) 670 642 Not-Attenuated Not-Essential
G723 1244 745 L-lactate dehydrogenase   (lldD2) 1921 1872 Attenuated Essential
G724 2282 1147 PPE family protein (PPE) 1599 1548 Not-Attenuated Not-Essential
G726 1655 590 conserved HP 2484 2411 Not-Attenuated Not-Essential
G727 2186 419 cell division control protein, putative 451 435 Not-Attenuated Not-Essential
G728 1871 418 HP 2289 2230 Not-Attenuated Not-Essential
G732 2300 662 molybdopterin oxidoreductase  (bisC) 1487 1442 Not-Attenuated Not-Essential
G745 1073 459 virulence factor mce family protein 3601 3497 Moderately-attenauated Essential
G747 1214 724 glucose-1-phosphate adenylyltransferase (glgC) 1251 1213 Not-Attenuated Not-Essential
G757 1913 732 DNA pol III, epsilon subunit, putative 2247 2191 Not-Attenuated Not-Essential
G763 1160 13 Thiolase (fadA6) 3660 3556 Not-Attenuated Not-Essential
G769 1424 349 conserved HP 3173 3088 Not-Attenuated Not-Essential
G773 815 427 immunogenic protein MPB64/MPT64 (mpt64) 2032 1980 Not-Attenuated Not-Essential
G779 470 179 HP 1922 1873 Not-Attenuated Not-Essential
G785 830 214 DNA binding response regulator TrcR 1062 1033 Not-Attenuated Not-Essential
G787 1703 508 HP  1035 1006 Not-Attenuated Not-Essential
G788 4862 1257 Polyketide synthase (pks1) 3018 2946 Not-Attenuated Not-Essential
G789 956 172 HP 1105 1075 Not-Attenuated Not-Essential
G790 671 247 HP 338 323 Not-Attenuated Not-Essential
G791 1007 755 3-oxoacyl-(acyl-carrier-protein) synthase III (fabH) 557 533 Not-Attenuated Not-Essential
G792 9560 2397 PPE family protein (PPE) 318 304 Not-Attenuated Not-Essential
G800 785 68 HP 2300 2240 Not-Attenuated Not-Essential
G802 9827 3661 PPE family protein (PPE) 370 355 Not-Attenuated Not-Essential
G804 2360 533 conserved HP 3509 3401 Not-Attenuated Not-Essential
G805 4475 1903 PPE family protein (PPE) 1968 1917 Not-Attenuated Not-Essential
G811 524 139 siderosphore binding protein, putative 3625 3525 Not-Attenuated Not-Essential
G813 398 72 HP 3964 3849 Not-Attenuated Not-Essential
G815 3269 68 membrane protein, mmpL family (mmpL8) 3931 3823 Attenuated Essential
G819 1229 484 IS 1553 transposase 3742 3640 Not-Attenuated Not-Essential
G824 1517 1176 HP 3584 3480 Not-Attenuated Not-Essential
G827 1721 347 ATPase, AAA family 3981 3868 Moderately-attenauated Essential
G828 1250 207 alkane-1-monooxygenase 3350 3252 Not-Attenuated Not-Essential
G829 923 593 conserved HP 1400 1357 Not-Attenuated Not-Essential
G832 383 114 HP 1810 1761 Not-Attenuated Not-Essential
G840 902 193 hydrolase, alpha/beta hydrolase fold family (HP) 3266 3177 Not-Attenuated Not-Essential
G846 608 187 IS1536, resolvase  (HP) 633 605 Not-Attenuated Not-Essential
G847 1049 326 biotin synthase (bioB) 1624 1589 Attenuated Essential
G849 1811 883 sulfatase family protein (atsF) 3162 3077 Not-Attenuated Not-Essential
G850 1349 72 lysine-epsilon aminotransferase (lat) 3389 3290 Not-Attenuated Not-Essential
G851 1076 76 DNA ligase, putative (ligC) 3836 3731 Not-Attenuated Not-Essential
G856 1895 1328 ABC transporter ATP-binding protein (HP) 1310 1272 Not-Attenuated Not-Essential
G857 284 12 Conserved HP 2411 2346 Not-Attenuated Not-Essential
G862 527 225 transcriptional regulatory, Mar family (HP) 1448 1404 Not-Attenuated Not-Essential
H915 977 484 HP 2637 2560 Not-Attenuated Not-Essential
H916 1751 1020 acyl-CoA synthase (fadD25) 1572 1521 Not-Attenuated Not-Essential
H917 1525 1019 HP 4001 3886 Not-Attenuated Not-Essential
H918 1586 912 PE family protein 1474 1430 Not-Attenuated Not-Essential
H919 599 24 chorismate mutase related protein  1933 1885 Not-Attenuated Not-Essential
H920 236 11 HP 2080.1 xxx Not-Attenuated Not-Essential
H922 626 84 HP 1082 xxx Not-Attenuated Not-Essential
H925 662 418 HP 1407 1362 Not-Attenuated Not-Essential
H929 191 114 HP 1520 xxx Not-Attenuated Not-Essential
H936 1571 184 spermidine synthase (speE) 2675 2601 Not-Attenuated Not-Essential
H954 728 36 Conserved HP 755 730 Not-Attenuated Not-Essential
J11 1562 588 Phospholipase C (plcA?) 2416 2351 Not-Attenuated Not-Essential
J16 2639 983 PE-PGRS protein 855 834 Not-Attenuated Not-Essential
J17 644 153 transcriptional regulator, TetR family 167 158 Not-Attenuated Not-Essential
J19 1286 1128 oxidoreductase, FAD binding 1821 1771 Not-Attenuated Not-Essential
J21 842 202 HP 2093 2033 Not-Attenuated Not-Essential
J23 1691 125 ATP-dependent RNA helicase (deaD) 1292 1253 Not-Attenuated Not-Essential
J24 2344 1639 HP 1179.1 1146 Not-Attenuated Not-Essential
J26 362 57 HP 766 740 Not-Attenuated Not-Essential
J29 1595 337 HP 1809 1760 Not-Attenuated Not-Essential
J30 1025 51 hydrolase, alpha-beta-hydrolase fold family 2788 2715 Not-Attenuated Not-Essential
J33 335 220 PE family protein 1233 1195 Not-Attenuated Not-Essential
J34 869 373 dioxygenase  106 97 Attenuated Essential
J35 434 163 HP 3478 3370 Not-Attenuated Not-Essential
J36 1628 228 Na+/H+ exchanger   (yjcE) 2345 2287 Not-Attenuated Not-Essential
J40 971 445 oxidoreductase 2355 2298 Not-Attenuated Not-Essential
J41 2654 432 Conserved HP 2643 2567 Moderately-attenauated Essential
J42 1523 1153 aldehyde dehydrogenase 474 458 Not-Attenuated Not-Essential
J134 281 77 Conserved HP 1376.1 1335 Not-Attenuated Not-Essential
J136 1952 74 acyl-CoA dehydrogenase (fadE10) 896 873 Not-Attenuated Not-Essential
J140 1601 202 PE-PGRS protein 1097 1068 Not-Attenuated Not-Essential
J143 2888 29 mmpL family protein, mmpL9 2402 2339 Not-Attenuated Not-Essential
SM1 1238 105 conserved HP 214 204 Attenuated Essential
SM3 1046 898 HP 2496 2423 Attenuated Essential
SM4 770 571 transcriptional regulator, TetR family 489 472 Moderately-attenauated Essential
G1 1583 179 Virulence factor (HP) 178 169 Not-Attenuated Not-Essential
G2 1514 739 PE_PGRS family protein (PE_PGRS) 3920 3812 Not-Attenuated Not-Essential
G4 2189 688 Lipopolysaccharide biosynthesis protein, WbpC 1616 1565 Not-Attenuated Not-Essential
G7 1406 796 Prolipoprotein diacylglycosyl transferase 1649 1614 Not-Attenuated Not-Essential
G8 377 202 HP 3776 3675 Not-Attenuated Not-Essential
G9 1601 466 PE family protein 161 152 Not-Attenuated Not-Essential
G10 1715 411 AMP binding family protein (fadD11) 1600 1550 Not-Attenuated Not-Essential
G16 1289 332 Transporter, NadC/P/Pho87 family (arsA) 2758 2684 Not-Attenuated Not-Essential
G26 380 15 HP 2932 2863 Not-Attenuated Not-Essential
G28 407 13 HP 3550 3445 Not-Attenuated Not-Essential
G35 2243 313 FtsK/SpoIIIE family protein 3983 3870 Not-Attenuated Not-Essential
G36 6335 150 Mycocerosic acid synthase (mas) 3010 2940 Not-Attenuated Not-Essential
G81 1661 9 Modification methylase 3363 3263 Not-Attenuated Not-Essential
G82 293 87 CBS domain protein 2478 2406 Not-Attenuated Not-Essential
G83 1769 655 HP 1475 1431 Not-Attenuated Not-Essential
G88 677 245 HP 2548 2473 Not-Attenuated Not-Essential
G92 1058 105 Conserved HP 2202 2143 Not-Attenuated Not-Essential
G95 1304 531 amino acid permease (HP) 544 522 Not-Attenuated Not-Essential
G132 1349 1048 P450 heme-thiolate protein 342 327 Not-Attenuated Not-Essential
G139 2018 618 Fatty acid desaturase,ferredoxin reductase 3658 3554 Not-Attenuated Not-Essential
G142 425 314 Conserved HP 2695 2620 Not-Attenuated Not-Essential
G146 383 236 HP 2778 2705 Not-Attenuated Not-Essential
G153 272 86 Exodeoxyribonuclease, small subunit 1138 1107 Not-Attenuated Not-Essential
G154 1016 722 Conserved HP 3903 3796 Not-Attenuated Not-Essential
G157 1382 530 Divalent cation transporter MgtE family (MgtE) 378 362 Not-Attenuated Not-Essential
G161 1904 418 Metallo-beta-lactamase superfamily protein 3869 3762 Not-Attenuated Not-Essential
G163 1982 1072 Cation-transporting ATPase, E1-E2 family 3851 3743 Not-Attenuated Not-Essential
G164 563 356 Conserved HP 1243 1205 Not-Attenuated Not-Essential
G168 2903 1217 mmpL4 466 450 Attenuated Essential
G177 1061 527 Transcriptional regulator, AraC family 3841 3736 Not-Attenuated Not-Essential
G199 434 326 Anti-anti sigma factor 1955 1904 Not-Attenuated Not-Essential
G215 710 523 Oxidoreductase 3087 3007 Not-Attenuated Not-Essential
G224 755 26 acyltransferase family protein 3924 3816 Not-Attenuated Not-Essential
G230 410 139 PiIB-related protein 2748 2673 Not-Attenuated Not-Essential
G254 311 125 HP 1134 1102 Not-Attenuated Not-Essential
G263 2762 630 mmpL7 3012 2942 Not-Attenuated Not-Essential
G274 1181 839 sugar ABC transporter  (sugC) 1276 1238 Attenuated Essential
G335 530 350 Conserved HP 2198 2140 Attenuated Essential
G413 1349 456 HP 231 221 Not-Attenuated Not-Essential
G415 1682 1091 Substrate CoA ligase (fadD2) 283 270 Not-Attenuated Not-Essential
G422 440 69 HP 2692 2617 Not-Attenuated Not-Essential
G433 1587 953 purple acid phosphotase - related protein (HP) 2654 2577 Not-Attenuated Not-Essential
G452 1334 300 PPE family protein 901 878 Not-Attenuated Not-Essential
G460 1967 714 PPE family protein 1849 1800 Not-Attenuated Not-Essential
G466 11355 1035 PPE family protein 3458 3350 Not-Attenuated Not-Essential
G467 857 528 HP 915 891 Not-Attenuated Not-Essential
G474 1388 742 L-asparagine permease 2186 2127 Not-Attenuated Not-Essential
G480 1766 84 PE family protein 160 151 Not-Attenuated Not-Essential
G488 1835 1604 HP 2981 2913 Not-Attenuated Not-Essential
G492 1166 909 Monooxygenase putative 604 575 Not-Attenuated Not-Essential
G500 1769 655 HP 1475 1431 Not-Attenuated Not-Essential
G504 476 352 Conserved HP 2299 2239 Attenuated Essential
G520 1283 1094 Thymidine phosphorylase (deoA) 3415 3314 Not-Attenuated Not-Essential
G522 893 546 Thiosulfate sulfurtransferase (sscA) 3382 3283 Attenuated Essential
G540 2444 1853 5-methyltetrahydrofolate - homocysteine (metH) 2183 2124 Not-Attenuated Not-Essential
G544 1914 109 Conserved HP 698 669 Not-Attenuated Not-Essential
G545 647 215 HP 1958 1907 Not-Attenuated Not-Essential
G546 1232 914 NADH dehydrogenase I, subunit H (nuoH) 3240 3152 Not-Attenuated Not-Essential
G557 465 299 HP 2871 2803 Not-Attenuated Not-Essential
G566 1751 954 Acyl-CoA-synthase 2999 2930 Attenuated Essential
G567 452 301 PPE family protein 2182.1 2123 Not-Attenuated Not-Essential
G532 2876 1222 mmpL1 412 402 Not-Attenuated Not-Essential
E168 2906 458 mmpL2 528 507 Not-Attenuated Not-Essential
H446 2906 2203 mmpL2 528 507 Not-Attenuated Not-Essential
G168 2903 1217 mmpL4 466 450 Attenuated Essential
G868 2894 1773 mmpL5 705 676 Not-Attenuated Not-Essential
R294 2894 899 mmpL5 705 676 Attenuated Essential
H293 1193 921 mmpL6 1608 1557 Not-Attenuated Not-Essential
G263 2762 630 mmpL7 3012 2942 Attenuated Essential
R285 3269 53 mmpL8 3931 3823 Attenuated Essential
G476 2888 29 mmpL9 2402 2339 Not-Attenuated Not-Essential
R61 3008 2828 mmpL10 1220 1183 Attenuated Essential
G46 2900 560 mmpL11 212 202 Attenuated Essential
G107 3440 349 mmpL12 1573 1522 Not-Attenuated Not-Essential
H353 3440 772 mmpL12 1573 1522 Not-Attenuated Not-Essential
E262 437 80 mmpS2 527 506 Not-Attenuated Not-Essential
L6 899 402 mmpS3 2254 2198 Not-Attenuated Not-Essential
H28 2381 322 GTP pyrophosphokinase (relA) 2660 2583 Attenuated Essential
H289 752 564 Conserved HP 2749 2675 Not-Attenuated Not-Essential
H524 224 106 HP 2606 2530 Not-Attenuated Not-Essential
H528 389 290 HP 1083 1052 Not-Attenuated Not-Essential
H545 2156 664 Protease II , ptrBa 805 781 Not-Attenuated Not-Essential
H551 1304 886 conserved HP 2525 2449 Not-Attenuated Not-Essential
H555 1619 1349 virulence factor mce protein 624 594 Not-Attenuated Not-Essential
H556 1226 138 IS 1537 Transposase 3935 3827 Not-Attenuated Not-Essential
H557 854 296 HP 2803.2 2734 Not-Attenuated Not-Essential
H561 1241 11 PE family protein 2404 2340 Not-Attenuated Not-Essential
H562 842 521 hydrolase/esterase, lpqP 700 671 Not-Attenuated Not-Essential
H570 179 19 HP 933 909 Not-Attenuated Not-Essential
H582 488 261 HP 488 471 Not-Attenuated Not-Essential
H615 1040 334 putative esterase, antigen 85-C 137 129 Attenuated Essential
H619 1080 683 ABC transporter, ATP binding protein 684 655 Attenuated Essential
H790 1316 180 NagC-related protein 503 485 Attenuated Essential
H794 1391 1254 nitrite exclusion protein 280 267 Not-Attenuated Not-Essential
H844 710 280 Conserved HP 2888 2821 Not-Attenuated Not-Essential
s14 1358 376 Conserved HP 2158 2097 Not-Attenuated Not-Essential
s16 587 288 HIT family protein 2688 2613 Not-Attenuated Not-Essential
s22 1646 1355 Peptide ABC-transporter (dppD) 3764 3663 Not-Attenuated Not-Essential
s26 128 73 HP 3145.1 3059 Not-Attenuated Not-Essential
s27 527 62 HP (b/w Rv 3142/3143) 3229 xx Not-Attenuated Not-Essential
s36 1829 482 ATPase AAA family 2175 2115 Not-Attenuated Not-Essential
s39 935 31 Integrase/recombinase XerD 1740 1701 Not-Attenuated Not-Essential
s41 1580 1043 MgmE/PrPD family protein 1162 1130 Not-Attenuated Not-Essential
s43 1829 893 ATPase AAA family 2175 2115 Not-Attenuated Not-Essential
s45 2538 2227 HP 4022 3903 Not-Attenuated Not-Essential
s48 230 43 HP 694 666 Attenuated Essential
s49 770 256 transcriptional regulator, TetR family 489 472 Attenuated Essential
s51 293 211 Conserved HP 529 508 Not-Attenuated Not-Essential
s52 1778 1132 oxidoreductase, short chain 2270 2214 Not-Attenuated Not-Essential
s53 1525 1019 HP 4001 3886 Not-Attenuated Not-Essential
s55 1076 934 magnesium chelatase, putative 3794 3692 Not-Attenuated Not-Essential
s57 1004 326 4-hydroxy-2-oxovalerate aldolase 3575 3469 Not-Attenuated Not-Essential
s59 1697 1467 2,3-dihydroxybenzoate- AMP ligase 2452 2384 Not-Attenuated Not-Essential
s63 1523 862 Proteinase, putative 2282 2224 Attenuated Essential
s67 962 511 D-amino acid oxidase (aao) 1956 1905 Not-Attenuated Not-Essential
s80 1553 1115 Glycerolkinase (glpK) 3798 3696 Not-Attenuated Not-Essential
R23 1271 658 Lipoprotein (lppF) 1972 1921 Not-Attenuated Not-Essential
R35 845 1 HP (b/w Rv3027/3028) 3111 3027 Not-Attenuated Not-Essential
R53 1598 348 Very-long-chain acyl-CoA-synthetase (fadD1) 1793 1750 Not-Attenuated Not-Essential
R64 902 442 HP 541 519 Not-Attenuated Not-Essential
R66 950 692 Conserved HP 2156 2095 Not-Attenuated Not-Essential
R83 1544 1105 phospholipase C (plcD) 1799 1755 Not-Attenuated Not-Essential
R92 1940 18 Exinuclease ABC, subunit C (uvrC) 1463 1420 Not-Attenuated Not-Essential
R97 401 117 Conserved HP 3230 3143 Not-Attenuated Not-Essential
R161 2363 571 Arylsulfatase (atsD) 692 663 Not-Attenuated Not-Essential
R164 344 172 transcriptional regulatorArsR family (HP) 88 81 Not-Attenuated Not-Essential
R169 1463 22 Aldehyde dehydrogenase family protein 233 223 Not-Attenuated Not-Essential
R175 1346 480 amino acylase-1, putative (dapE2)  2199 2141 Not-Attenuated Not-Essential
R181 3441 1124 HP 1290 1251 Not-Attenuated Not-Essential
R182 1424 1132 Conserved HP 3352 3254 Not-Attenuated Not-Essential
R189 1202 810 Non-specific lipid transfer protein (ltp1) 2860 2790 Not-Attenuated Not-Essential
R197 2171 102 HP 3993 3879 Not-Attenuated Not-Essential
R204 1406 1039 oxidoreductase, pyridine nucleotide-disulphide 2786 2713 Not-Attenuated Not-Essential
R208 1034 585 IS1603 transposase 3281 3191 Not-Attenuated Not-Essential
R220 998 304 Cation efflux system protein (HP) 2084 2025 Not-Attenuated Not-Essential
R223 1319 143 HP 465 449 Not-Attenuated Not-Essential
R235 1037 355 Parathion hydrolase (HP) 240 230 Not-Attenuated Not-Essential
R237 1619 601 Chaperonin 69kDa (groEL1) 3526 3417 Attenuated Essential
R240 1145 212 N5, N10 methylenetetrahydromethanopterin reductase related protein 3025 2951 Not-Attenuated Not-Essential
R243 1511 1221 HP 350 336 Attenuated Essential
R245 1163 262 Glycosyl transferase 1250 1212 Not-Attenuated Not-Essential
R252 2174 1612 4-a-gluconotransferase 1831 1781 Attenuated Essential
R253 1073 481 GTP binding protein 1143 1112 Not-Attenuated Not-Essential
R254 674 9 RNA polymerase sigma 70 factor, ECF family  3523 3414 Not-Attenuated Not-Essential
R258 1145 932 HP 3793 3691 Not-Attenuated Not-Essential
R259 830 466 Conserved HP 4004 3889 Not-Attenuated Not-Essential
R265 1151 949 HP 3632 3529 Not-Attenuated Not-Essential
R266 1646 518 Substrate CoA-ligase, putative (fadD19) 3616 3515 Not-Attenuated Not-Essential
R268 392 268 HP 2944 2877 Not-Attenuated Not-Essential
R274 212 67 Conserved HP 3853 3745 Not-Attenuated Not-Essential
R275 1775 630 ABC transporter, ATP-binding protein (HP) 1707 1668 Not-Attenuated Not-Essential
R277 698 441 HP 3769 3668 Not-Attenuated Not-Essential
R284 1223 91 Acyl-CoA-dehydrogenase, putative (fadE2) 163 154 Not-Attenuated Not-Essential
R287 1682 515 Indolepyruvate decarboxylase, putative 876 853 Attenuated Essential
R289 2063 1 Drug transporter (HP) 1926 1877 Not-Attenuated Not-Essential
R295 644 35 HP 3808 3705 Not-Attenuated Not-Essential
Text Box: Legend:
ID: Unique identification label for each mutant
Gene size: Size of the gene in base pairs
POI: Point of Insertion: This is the location from the putative translation start site where the transposon has inserted.
Gene description: Functional description of the gene mutated
MT#: A unique gene annotation number assigned by TIGR database for M. tuberculosis CDC1551.
Rv#: A unique gene annotation number assigned by Sanger database for M. tuberculosis H37Rv.
Output/Input: this value represents the ratio of probe for each mutant in the output and input pools
Data obtained at 20 days post infection were similar for most mutants, and thus not as decisive as that obtained at 49 days (data not shown)
n/a: data not available. 
NOTE: both input/output ratios and P-values should be compared only within each pool used in infection as the input/output signals were normalized accordingly. 
Mutants that were attenuated for in vivo growth are labeled in blue. Those that are likely to be involved in attenuation are labeled green and false positives are labeled red.