TARGET now has more than 4300 unique transposon mutants!!! Click here to browse our mutant collection Click here to order mutants from BEI Search our Mutants Latest Hits!!! Rv1874 Rv0241c Rv2565 Rv2417c Rv0584 Rv2258c Updated May 12, 2009

Details Description POSSIBLE 8-AMINO-7-OXONONANOATE SYNTHASE BIOF2 (AONS) (8-AMINO-7-KETOPELARGONATE SYNTHASE) (7-KETO-8-AMINO-PELARGONIC ACID SYNTHETASE) (7-KAP SYNTHETASE) (L-ALANINE--PIMELYL CoA LIGASE) Accession number Rv0032 Gene name bioF2 Gene length 2316 Protein length 771 Coordinates 34295..36610 Orientation + Molecular mass 86243.03 Isoelectric point 7.02 Database Crossreferences Click Here Click Here Click Here Click Here Deletion Mutant Phenotype in-vivo guinea pig   mouse   rabbit in-vitro HBMEC   macrophage Mutant Survival in DeADMAn (Lamichhane et al., 2005)* Strain Name Phenotype (Mouse) JHU0032-394 [no data] JHU0032-2161 [no data] JHU0032-2032 [no data] JHU0032-781 [no data]   CDC1551 Homolog ORF MT0037 Essentiality Prediction Sassetti et al, 2003* non-essential JHU Transposon Mutant(s) Available Name MT# Rv# POI Gene Length Available from BEI JHU0032-2161 MT0037 Rv0032 2161 2316 no (will be available later) JHU0032-2032 MT0037 Rv0032 2032 2316 no (will be available later) JHU0032-781 MT0037 Rv0032 781 2316 yes    For a list of currently available mutants, please visit BEI's transposon mutant webpage. If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request. References Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text] Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text] Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40. [Abstract/Free Full Text]