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Johns Hopkins Center for TB Research Johns Hopkins School of Medicine

TARGET now has more than 4300 unique transposon mutants!!!
Click here to browse our mutant collection
Click here to order mutants from BEI
Search our Mutants

Latest Hits!!!
Rv1874 Rv0241c
Rv2565 Rv2417c
Rv0584 Rv2258c
Updated May 12, 2009
Details
DescriptionMONOOXYGENASE ETHA
Accession numberRv3854c
Gene nameethA
Gene length1470
Protein length489
Coordinates4326004..4327473
Orientation-
Molecular mass55325.98
Isoelectric point8.33

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3854c-632[no data]
JHU3854c-631[no data]
JHU3854c-1381[no data]
JHU3854c-631[no data]
JHU3854c-422[no data]
JHU3854c-703[no data]
JHU3854c-1468[no data]
 

CDC1551 Homolog
ORFMT3969
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3854c-632MT3969Rv3854c6321470no (will be available later)
JHU3854c-1381MT3969Rv3854c13811470no (will be available later)
JHU3854c-631MT3969Rv3854c6311470no (will be available later)
JHU3854c-422MT3969Rv3854c4221470no (will be available later)
JHU3854c-703MT3969Rv3854c7031470yes
JHU3854c-1468MT3969Rv3854c14681470no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]