TARGET now has more than 4300 unique transposon mutants!!! Click here to browse our mutant collection Click here to order mutants from BEI Search our Mutants Latest Hits!!! Rv1874 Rv0241c Rv2565 Rv2417c Rv0584 Rv2258c Updated May 12, 2009

Details Description PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Accession number Rv0270 Gene name fadD2 Gene length 1683 Protein length 560 Coordinates 324567..326249 Orientation + Molecular mass 59892.48 Isoelectric point 6.76 Database Crossreferences Click Here Click Here Click Here Click Here Deletion Mutant Phenotype in-vivo guinea pig   mouse   rabbit in-vitro HBMEC   macrophage Mutant Survival in DeADMAn (Lamichhane et al., 2005)* Strain Name Phenotype (Mouse) JHU0270-1091 Not-Attenuated JHU0270-65 [no data]   CDC1551 Homolog ORF MT0283 Essentiality Prediction Sassetti et al, 2003* non-essential JHU Transposon Mutant(s) Available Name MT# Rv# POI Gene Length Available from BEI JHU0270-65 MT0283 Rv0270 65 1683 yes    For a list of currently available mutants, please visit BEI's transposon mutant webpage. If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request. References Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text] Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text] Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40. [Abstract/Free Full Text]