TARGET now has more than 4300 unique transposon mutants!!! Click here to browse our mutant collection Click here to order mutants from BEI Search our Mutants Latest Hits!!! Rv1874 Rv0241c Rv2565 Rv2417c Rv0584 Rv2258c Updated May 12, 2009

Details Description PROBABLE RIBOSE-PHOSPHATE PYROPHOSPHOKINASE PRSA (Phosphoribosyl pyrophosphate synthetase) (PRPP synthetase) Accession number Rv1017c Gene name prsA Gene length 981 Protein length 326 Coordinates 1135501..1136481 Orientation - Molecular mass 35459.34 Isoelectric point 6.51 Database Crossreferences Click Here Click Here Click Here Click Here Deletion Mutant Phenotype in-vivo guinea pig   mouse   rabbit in-vitro HBMEC   macrophage Mutant Survival in DeADMAn (Lamichhane et al., 2005)* Strain Name Phenotype (Mouse) [not tested] [no data]   CDC1551 Homolog ORF MT1045 Essentiality Prediction Sassetti et al, 2003* essential JHU Transposon Mutant(s) Available Sorry, no mutants available.    For a list of currently available mutants, please visit BEI's transposon mutant webpage. If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request. References Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text] Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text] Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40. [Abstract/Free Full Text]