TARGET now has more than 4300 unique transposon mutants!!! Click here to browse our mutant collection Click here to order mutants from BEI Search our Mutants Latest Hits!!! Rv1874 Rv0241c Rv2565 Rv2417c Rv0584 Rv2258c Updated May 12, 2009

Details Description PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Accession number Rv1258c Gene name Rv1258c Gene length 1260 Protein length 419 Coordinates 1406081..1407340 Orientation - Molecular mass 43287.2 Isoelectric point 9.54 Database Crossreferences Click Here Click Here Click Here Click Here Deletion Mutant Phenotype in-vivo guinea pig   mouse   rabbit in-vitro HBMEC   macrophage Mutant Survival in DeADMAn (Lamichhane et al., 2005)* Strain Name Phenotype (Mouse) JHU1258c-997 [no data] JHU1258c-833 [no data] JHU1258c-715 [no data] JHU1258c-973 [no data]   CDC1551 Homolog ORF MT1297 Essentiality Prediction Sassetti et al, 2003* non-essential JHU Transposon Mutant(s) Available Name MT# Rv# POI Gene Length Available from BEI JHU1258c-997 MT1297 Rv1258c 997 1260 yes JHU1258c-833 MT1297 Rv1258c 833 1260 no (will be available later) JHU1258c-715 MT1297 Rv1258c 715 1260 no (will be available later) JHU1258c-973 MT1297 Rv1258c 973 1260 no (will be available later)    For a list of currently available mutants, please visit BEI's transposon mutant webpage. If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request. References Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text] Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text] Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40. [Abstract/Free Full Text]