target banner
Johns Hopkins Center for TB Research Johns Hopkins School of Medicine

TARGET now has more than 4300 unique transposon mutants!!!
Click here to browse our mutant collection
Click here to order mutants from BEI
Search our Mutants

Latest Hits!!!
Rv1874 Rv0241c
Rv2565 Rv2417c
Rv0584 Rv2258c
Updated May 12, 2009
Details
DescriptionPROBABLE NAD-DEPENDENT GLUTAMATE DEHYDROGENASE GDH (NAD-GDH) (NAD-DEPENDENT GLUTAMIC DEHYDROGENASE)
Accession numberRv2476c
Gene namegdh
Gene length4875
Protein length1624
Coordinates2777388..2782262
Orientation-
Molecular mass176899.69
Isoelectric point5.58

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2476c-92[no data]
JHU2476c-3334[no data]
 

CDC1551 Homolog
ORFMT2551
Essentiality Prediction
Sassetti et al, 2003*[no data]

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2476c-92MT2551Rv2476c924875yes
JHU2476c-3334MT2551Rv2476c33344875no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]