TARGET now has more than 4300 unique transposon mutants!!! Click here to browse our mutant collection Click here to order mutants from BEI Search our Mutants Latest Hits!!! Rv1874 Rv0241c Rv2565 Rv2417c Rv0584 Rv2258c Updated May 12, 2009

Details Description PROBABLE ISOCITRATE DEHYDROGENASE [NADP] ICD1 (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) Accession number Rv3339c Gene name icd1 Gene length 1230 Protein length 409 Coordinates 3724615..3725844 Orientation - Molecular mass 45513.66 Isoelectric point 4.93 Database Crossreferences Click Here Click Here Click Here Click Here Deletion Mutant Phenotype in-vivo guinea pig   mouse   rabbit in-vitro HBMEC   macrophage Mutant Survival in DeADMAn (Lamichhane et al., 2005)* Strain Name Phenotype (Mouse) JHU3339c-745 [no data] JHU3339c-134 [no data] JHU3339c-98 [no data]   CDC1551 Homolog ORF MT3442 Essentiality Prediction Sassetti et al, 2003* non-essential JHU Transposon Mutant(s) Available Name MT# Rv# POI Gene Length Available from BEI JHU3339c-134 MT3442 Rv3339c 134 1230 no (will be available later) JHU3339c-98 MT3442 Rv3339c 98 1230 yes    For a list of currently available mutants, please visit BEI's transposon mutant webpage. If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request. References Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text] Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text] Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40. [Abstract/Free Full Text]