TARGET now has more than 4300 unique transposon mutants!!! Click here to browse our mutant collection Click here to order mutants from BEI Search our Mutants Latest Hits!!! Rv1874 Rv0241c Rv2565 Rv2417c Rv0584 Rv2258c Updated May 12, 2009

Details Description POSSIBLE dTDP-GLUCOSE 4,6-DEHYDRATASE Accession number Rv3784 Gene name Rv3784 Gene length 981 Protein length 326 Coordinates 4230256..4231236 Orientation + Molecular mass 36305.63 Isoelectric point 7.77 Database Crossreferences Click Here Click Here Click Here Click Here Deletion Mutant Phenotype in-vivo guinea pig   mouse   rabbit in-vitro HBMEC   macrophage Mutant Survival in DeADMAn (Lamichhane et al., 2005)* Strain Name Phenotype (Mouse) JHU3784-905 [no data] JHU3784-1772 [no data] JHU3784-7 [no data] JHU3784-328 [no data] JHU3784-1700 [no data] JHU3784-440 [no data] JHU3785-1773 [no data] JHU3784-1773 [no data] JHU3784-652 [no data]   CDC1551 Homolog ORF MT3893 Essentiality Prediction Sassetti et al, 2003* non-essential JHU Transposon Mutant(s) Available Name MT# Rv# POI Gene Length Available from BEI JHU3784-440 MT3893 Rv3784 440 2139 no (will be available later) JHU3784-652 MT3893 Rv3784 652 2139 no (will be available later)    For a list of currently available mutants, please visit BEI's transposon mutant webpage. If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.  Please click here  to submit a request. References Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text] Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text] Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40. [Abstract/Free Full Text]